On Air with Ryan Seacrest & Sisanie

Weekdays 2 - 6P and Don't miss the Seacrest Top 5 every day at 4 pm.


Ryan Seacrest is a creative entrepreneur and holds preeminent positions as a host and producer in nationally syndicated and local radio, as well as broadcast and cable television.

On radio, Seacrest is host of “On Air with Ryan Seacrest,” his market-topping #1 nationally syndicated LA morning drive-time show for iHeartMedia’s 102.7 KIIS-FM, as well as the nationally-syndicated “On Air with Ryan Seacrest,” “American Top 40 with Ryan Seacrest,” and the weekday vignette “Direct from Hollywood.”  For his work in radio, he was honored with the 2011 NAB Marconi Award for “Network Syndicated Personality of the Year,” and he was inducted in the prestigious Radio Hall of Fame in 2019.

Seacrest is a host and executive producer of the Disney/ABC syndicated “Live with Kelly and Ryan,” daily entertainment talk show, alongside Kelly Ripa. He is also host of the iconic music competition series “American Idol” on ABC. Additionally, Seacrest hosts and executive produces the annual live ABC broadcast of “Dick Clark’s Rockin’ New Year’s Eve with Ryan Seacrest.”

Seacrest helms Ryan Seacrest Productions (RSP) an Emmy-winning entertainment production company. RSP produces the E! hit cable series “Keeping Up with the Kardashians,” which celebrates its 20th  and final season in 2021, and its spin-offs, as well as Bravo’s “Shahs of Sunset,” and the upcoming TV movie, “Work Wife.” Additionally, RSP produced “Shades of Blue,” an NBC drama series starring Jennifer Lopez; “Insatiable” for Netflix; and the Emmy Award-winning reality series “Jamie Oliver’s Food Revolution.”

As an entrepreneur Seacrest has a burgeoning lifestyle enterprise, which includes a menswear collection, Ryan Seacrest Distinction, and a men’s skincare line, Polished by Dr. Lancer, in partnership with renowned dermatologist Dr. Harold Lancer. He has also several investments in media and technology companies including Headspace and ATTN:, among others.

His philanthropic efforts include serving as chairman of the Ryan Seacrest Foundation (RSF), which has opened ten broadcast media centers – Seacrest Studios – in pediatric hospitals in cities across the country. He also serves on the board of the Los Angeles County Museum of Art (LACMA) and as honorary chair of the Grammy Museum Foundation.



Sisanie is co-host of the top-rated On Air with Ryan Seacrest, a nationally syndicated four-hour music and entertainment news program that airs Monday through Friday between 10 a.m. and 7 p.m. local time. The program focuses on all aspects of the entertainment industry, including highlights and interviews with top talent from the worlds of music, film and television.  On Air can be heard on 160 stations worldwide, including major U.S. cities such as New York, Chicago, Philadelphia, Dallas, San Francisco, Boston, and Washington, D.C.  Internationally, the program can be heard in markets such as London, Sydney, Melbourne, Toronto, Vancouver, Montreal, Dubai, Beijing and many others.

In addition, Sisanie is co-host of On Air with Ryan Seacrest on KIIS-FM/Los Angeles.  The local morning show is one of the most-listened-to programs in Southern California. In July 2022, she was named Music Director for KISS-FM. She also hosts the Twinning with Sisanie podcast available on iHeartRadio and other platforms.

Prior to joining On Air in December 2015, Sisanie hosted her own midday show on KIIS-FM for eight years and also broadcasted a midday show for KHTS-Channel 93.3, San Diego’s Hit Music Station. Sisanie also hosted her own national show, which was heard on more than 60 CHR radio stations including major markets such as Y100 in Miami.

Born in Orange County, Calif, the bilingual, Mexican/Peruvian beauty discovered her passion for broadcasting in high school. Sisanie was only 19 years old when she started interning for iHeartMedia. She later worked part-time at both Top 40 station KHTS-FM and sister Country station KUSS-FM in San Diego, while earning a bachelor’s degree from San Diego State University. During that time, she also worked as a fill-in jock for Top 40 station XL 106.7 in Orlando and commuted to Los Angeles on weekends for a part-time on-air shift at 102.7 KIIS-FM.

Sisanie was honored by Edison Media Research in 2008 as one of its “30 under 30” after a nationwide search for 30 young bright individuals with promising careers in the radio industry.   Sisanie was the announcer for the 2014 and 2015 iHeartRadio Ultimate Pool Party which was nationally televised on The CW network. She has co-hosted LIVE From the Grammy Red Carpet for KTLA 5, and has filled-in as a co-host on ABC’s LIVE with Ryan &Kelly. She has also served as an entertainment correspondent for EXTRA.

Sisanie resides in Los Angeles with her husband three children. Fans can follow @Sisanie on Twitter and Instagram, or Facebook.